Evaluation of Antioxidant properties of Convolvulus pluricaulis extract

Arkava Das, Nandini Poyra, Rania Indu, Sangita Bhattacharya, Moumita Ray, Anjan Adhikari*

Department of Pharmacology, R G Kar Medical College, Kolkata-700004, West Bengal, India

*Address of correspondence: dradhikarianjankolkata@gmail.com

ABSTRACT

Objectives:Convolvulus pluricaulishas been widely used in traditional medicine as brain tonic, laxative, rejuvenator. The present study was planned to evaluate the antioxidant effects of Shankhapushpi or Convolvulus pluricaulis(CP).

Methods: Deactivation of free radicals by Convolvulus pluricaulis was studied by in vitro biochemical assays including 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide and superoxide radical and nitric oxide scavenging activities.

Results:Convolvulus pluricaulisshowed significant antioxidant properties. Dose-dependent antioxidant properties were noted. IC50 (Inhibitory Concentration) of Convolvulus pluricaulis for DPPH, hydrogen peroxide and superoxide radical were found to be 434.78 µg/ml, 7.82 µg/ml and 132.18 µg/ml.respectively.

Conclusion:  Antioxidant properties exhibited by the Convolvulus pluricaulismay be due to the presence of phytochemicals in the plant extract.

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